Non-viral vector is the use of non-viral vector material physical and chemical properties to mediate gene transfer. Shenzhen Cell Valley mainly provides a unique non-viral genetic engineering technology (PiggyBac transposon modification), which is the core technology for the development of CAR T therapy. PiggyBac efficiently delivers large amounts of genetic material to T cells and can produce CAR-T products with a high percentage of dry memory cells. It includes four subtypes: single gene, single promoter double gene (IRES), double promoter double gene and double promoter double gene (WPRE).
Product advantages of this series:
① The non-viral vector has a large load and can effectively transfer large genes and a variety of AR and CR molecules;
② Low toxicity and low immune response;
③ High transfection efficiency and stable expression;
④ Higher production efficiency and lower production cost.
Shenzhen Cell Valley Bio-pharmaceutical Co., Ltd. is a one-stop comprehensive outsourcing service providerfocusing on the cell and gene therapy industry in China, and also the only CRO / CDMO company with the industrial production of clinical grade retroviral carrier GMP. Shenzhen Cell Valley with standardized, industrialized production capabilities.It mainly includes production lines for CAR-T, CAR-NK, CAR-M, mesenchymal stem cells, and astrocytes, as well as several cell raw material production lines, including genetically engineered antibodies, cytokines, exosomes, and viral vectors.Which including retroviral vectors, lentiviral vectors, adenoviral vectors, and adeno-associated viral vectors, and also provides IIT and IND application support services.